Case Study
How UCSF Is Building Confidence in Outpatient Advanced Therapies
UCSF Health launched outpatient and hybrid pathways for CAR‑T, bispecific and autologous BMT patients, supported by Current Health’s passive monitoring and 24/7 nurse oversight.
THE OPPORTUNITY
Advanced therapy demand is outgrowing inpatient beds
CAR‑T and bispecific therapies have meant long, planned inpatient stays for post‑infusion and step-up dosing (SUD) monitoring — occupying valuable beds for days or weeks. UCSF wanted to expand access and protect margin without compromising safety or clinical oversight.
Bed bottleneck
High-value bed requirements for post-infusion monitoring limited the volume of advanced therapy cases that UCSF could accommodate.
Capped throughput
With volume limited by inpatient capacity, referral demand became a ceiling instead of an opportunity to grow.
Uncompromised oversight
Moving care home only works if the clinical team keeps continuous visibility and can escalate the moment it matters.
HOW THE PROGRAM WORKS
Advanced therapy demand is outgrowing inpatient beds
Eligible patients go home after infusion with a Current Health kit. Passive monitoring and a dedicated nurse team do the watching, catching deterioration early and escalating to the UCSF clinical team according to program protocols.
01
ENROLL
Identify & equip
Patients are selected based off established clinical criteria and enrolled in a pathway created for their specific diagnosis, Car T, Bispecific, and auto transplant. They are then educated and fitted with the Current Health wearable before discharge.
02
MONITOR
Passive vitals at home
The wearable streams heart rate, respiratory rate, SpO2 and skin temperature continuously — surfacing physiological signals of CRS earlier than a single spot temperature check and preventing burdens on caregivers to identify adverse events.
03
RESPOND
24/7 Clinical Command Center
Current Health nurses triage every alarm in real time, contact patients directly, and triage, resolve or escalate to the UCSF team per site protocols, resolving, the majority of clinical concerns without needing to reach out to HCPs.
BY THE NUMBERS
The first six months at UCSF
Program data across CAR‑T, bispecific and transplant pathways, monitored for an average of six days each.
23
Patients managed on the platform in the first six months.
231
Inpatient bed days saved — every one backfilled by another heme/BMT patient needing inpatient care.
85%
Of clinical concerns managed without escalation to a provider.
22%
Of patients had no clinical alarms.
The economics
Saved beds, backfilled the same day
By moving post‑infusion monitoring home, UCSF recognized cost savings from 340B and outpatient pricing — and freed beds while increasing volume. Returned inpatient capacity was backfilled, accelerating throughput.
6
Average days monitored per patient across all pathways.
100%
Of saved bed days redeployed to other heme/BMT patients needing acute care.
“Current Health delivers 24/7 nurse oversight and dedicated remote triage. They're always watching our patients — so we know when we can't be there, Current Health can.”
Tricia Estacio, RN
Director of Nursing, Parnassus Infusion & Apheresis
UCSF Medical Center
WHAT'S NEXT
Proven safe, now widening the door
UCSF launched the outpatient and hybrid pathways with deliberately narrow eligibility criteria and a conservative, safety‑first rollout. With the model proven over the first six months, the team is now revisiting those criteria to bring more patients onto the outpatient pathway.
Start conservative
UCSF opened with careful eligibility criteria, keeping the first outpatient cohorts small while accruing clinician confidence in the model.
Prove it out
Early results held up: patients did well in the outpatient setting and the safety net performed — giving the team confidence in who could be managed at home.
Widen the door
With the model proven, UCSF is reviewing its eligibility criteria to move more patients outpatient, using hybrid pathways for the higher risk patients.
watch the webinar
Migrating Advanced Therapies Outpatient: Operational Insights from UCSF
Hear UCSF’s Janelle Smith Hernandez and Tricia Estacio walk through how they built their inpatient‑outpatient (IPOP) model — the selection criteria, the staffing, and the first‑six‑month results — in conversation with Current Health CMO Dr. Matt Wilkes.
