Now available – Integrated Virtual ICANS Assessments Find out more.
Now available – Integrated Virtual ICANS Assessments Find out more.
Analyzing the quality, experiences, and operations of outpatient delivery of CAR-T and bispecific therapies.
Analyzing complex and acute inpatient-equivalent care within Hospital at Home and Virtual Ward programs.
Analyzing operations and outcomes for all other clinical use cases for complex care at home.
Digital Biomarkers of Cytokine Release Syndrome: Scoping Review and Ontology Development of the Role and Relevance of Digital Measures Using a Mixed Methods Approach.
Insight: Digital biomarkers and remote monitoring can meaningfully detect and track early signs of cytokine release syndrome. Standard definitions, ontologies, and validation frameworks are needed to enable consistent clinical and regulatory adoption.
Medberry C, Angel C, Batavia A, Bradley S, Camerlingo N, Chen M, Datoo M, Kamdar P, Koenig E, Kusters L, Marquez C, Nukala U, Pettinati M, Phillips R, Sanchez D, Shafagati N, Siegelman J, Stewart M, Varga C, Vandendriessche B, Wilkes M, Wolff-Hughes D, Zahavi D, Zorman S, McClenahan S. Digital Biomarkers of Cytokine Release Syndrome: Scoping Review and Ontology Development of the Role and Relevance of Digital Measures Using a Mixed Methods Approach. J Med Internet Res 2025;27:e71956.
Optimization of Remote Patient Monitoring in the Outpatient Setting after Lisocabtagene Maraleucel (Liso-cel): Alarm Patterns and Hospitalization in a Multicenter Cohort.
Insight: RPM preserves safety outcomes while optimizing healthcare resource utilization. 39% of patients were successfully managed without hospitalization. All CRS/ICANS hospitalization occurred in the first 10 days.
Battiwalla M, Nadimpalli G, Arnold Egloff S, Martin C, Wilkes M, Farhadfar N, Rao U, Tees M, Patel K, Daniel L, Liu FF, Botros A, Charafi L, Blunk B, Henkel M, Mattlin M, Roy D, Zahradka N, Amin P, Kumar J, Cox T, Billups R, Majhail N. Optimization of Remote Patient Monitoring in the Outpatient Setting after Lisocabtagene Maraleucel (Liso-cel): Alarm Patterns and Hospitalization in a Multicenter Cohort. ASTCT Tandem 2026 (accepted).
Effectiveness of remote patient monitoring in enabling outpatient step-up dosing for bispecifics at a large academic cancer center in the USA.
Insight: Outpatient RPM enabled safe step-up dosing of bispecific therapies by identifying CRS and escalating to appropriate care in a timely manner, reducing resource utilization.
Rajeeve S, Wilkes M, Zahradka N, Deshpande M, Wang A, Hamadeh I, Aliaga K, Jones K, Maclachlan K, Hasmi H, Tan C, Hultcrantz M, […], Korde, N. Effectiveness of remote patient monitoring in enabling outpatient step-up dosing for bispecifics at a large academic cancer center in the USA. Blood. 2025; 146 (Suppl 1): 2751.
Remote Patient Monitoring for 15 Vs. 30 Days in Outpatient Chimeric Antigen Receptor T-Cell Therapy (CAR-T) across a Large Health System.
Insight: A 15-day RPM period is sufficient for capturing nearly all serious adverse events related to FDA-approved CAR-T products, supporting a shorter, efficient monitoring approach.
Cox T, Zahradka N, Martin C, Blunk B, Billups R, Meissner S, Sowell H, Larson S, Perez M, Ramakrishnan A, Shaughnessy P, Smith A, Tees M, Pantin J, Zaniello B, Majhail N, Battiwalla M. Remote Patient Monitoring for 15 Vs. 30 Days in Outpatient Chimeric Antigen Receptor T-Cell Therapy (CAR-T) across a Large Health System. Transplantation and Cellular Therapy. 2025; 31 (2), S223 – S224.
Outpatient Administration of Chimeric Antigen Receptor T-cell Therapy Using Remote Patient Monitoring
Insight: Successful outpatient care depends on multidisciplinary teams, rapid response protocols for managing toxicities like CRS and ICANS, and efficient patient transitions to higher level care when needed. RPM enables scalable, cost effective models that can expand access, reduce hospital stays, and improve patient and caregiver experiences.
Majhail NS, Cox T, Larson S, Battiwalla M, Ramakrishnan A, Shaughnessy P, Tees M, Zahradka N, Wilkes M, Pantin J. Outpatient Administration of Chimeric Antigen Receptor T-cell Therapy Using Remote Patient Monitoring. JCO Oncol Pract. 2025 April 18:OP2500062.
Comparison of 15- vs. 30-day remote patient monitoring for outpatient Chimeric Antigen Receptor T-cell Therapy (CAR-T) across a large health system.
Insight: Remote monitoring duration in outpatient CAR-T. For patients receiving currently FDA approved CAR-T products, RPM monitoring for first 15 days captures the majority of CRS and ICANS.
Cox T, Zahradka N, Martin C, Blunk B, Billups R, Meissner S, Sowell H, Larson S, Perez M, Ramakrishnan A, Shaughnessy P, Smith A, Tees M, Pantin J, Zaniello B, Majhail N, Battiwalla M. Comparison of 15- vs. 30-day remote patient monitoring for outpatient Chimeric Antigen Receptor T-cell Therapy (CAR-T) across a large health system. Blood. 2024; 144 (Suppl 1): 2300.
Remote patient monitoring (RPM) technology with centralized virtual nurse monitoring for safe delivery of outpatient chimeric antigen receptor T-cell (CAR-T) therapy across multiple Sarah Cannon Transplant and Cellular Therapy, 30 Network Programs.
Insight: Feasibility and logistics of a standardized outpatient CAR-T program. Sarah Cannon’s experience deploying their standardized pathways across 4 sites and the virtual component that supported care outside of clinic hours.
Cox T, Carelock T, Zahradka N, Pugmire J, Wilkes M, Campo R, Garber S, Yates M, Perez M, Husband M, Martin C, Blunk B, Billups RL, LeMaistre CF, Pantin J, Ramakrishnan A, Shaughnessy P, Tees MT, Majhail N, Battiwalla M. Remote patient monitoring (RPM) technology with centralized virtual nurse monitoring for safe delivery of outpatient chimeric antigen receptor T-cell (CAR-T) therapy across multiple Sarah Cannon Transplant and Cellular Therapy, 30 Network Programs. Transplantation and Cellular Therapy. 2024; 30(2): S216-S217.
A prospective, multi-institutional digital health pilot study to detect pneumonitis early in patients with stage III NSCLC on durvalumab monitored remotely: findings from the ON TRAX study
Insight: Detection of early signs of pneumonitis. The prospective pilot study demonstrated the potential in predicting pneumonitis in patients receiving durvalumab with a multiparametric remote monitoring system.
Cotarla I, Saltos AN, Peikert TD, Tannenwald B, Hsieh K, Irabor OC, Frankart AJ, Bhosale A, Zahradka N, Wilkes M, Gray J. A prospective, multi-institutional digital health pilot study to detect pneumonitis early in patients with stage III NSCLC on durvalumab monitored remotely: findings from the ON TRAX study. International Journal of Radiation Oncology*Biology*Physics. 2024;118(1):e8-e9.
Outpatient blinatumomab with digital monitoring in patients with measurable residual disease positive (MRD+) B-ALL in a phase 4 study.
Insight: Outpatient administration of cIV blinatumomab in patients with MRD+ B-ALL was feasible and safe with appropriate outpatient digital monitoring.
Pardee T, Varela J, Jeyakumar D, Keng MK, Bar-Natan M, Gundabolu K, Gayle A, McCann C, Xia Q, Ganzha S, Mergen N, Zaman F, Gordon P, Khan S. Outpatient blinatumomab with digital monitoring in patients with measurable residual disease positive (MRD+) B-ALL in a phase 4 study. J Clin Oncol. 2024; 42: 6544.
Early and consistent CRS detection using wearable device for remote patient monitoring following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM): early results of an investigator-initiated trial.
Insight: Increased sample size in early detection of cytokine release syndrome analysis. Detection of initial episode of cytokine release syndrome using wearable occurred 1.7 hours earlier than standard of care.
Rajeeve S, Zahradka N, Wilkes M, Pan D, Calafat N, Serebyrakova K, Kappes K, Jackson H, Buchenholz N, Agte S, Thibaud S, Sanchez LJ, Richard S, Richter JR, Rodriguez C, Cho HJ, Chari A, Jagannath S, Rossi A, Parekh SS. Early and consistent CRS detection using wearable device for remote patient monitoring following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM): early results of an investigator-initiated trial. Blood. 2023; 142: S1007.
Leveraging wearable devices for remote patient monitoring facilitate earlier CRS detection following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM): Early results from an IIT.
Insight: Early detection of cytokine release syndrome and subclinical events using wearable devices. Detection of initial episode of cytokine release syndrome using wearable occurred 2.1 hours earlier than standard of care. Individualized temperature thresholds facilitate earlier detection of CRS than fixed thresholds in patients receiving CAR-T therapy for relapsed/refractory multiple myeloma.
Rajeeve S, Wilkes M, Zahradka N, Calafat N, Serebyrakova K, Kappes K, Jackson H, Buchenholz N, Agte S, Thibaud S, Sanchez LJ, Richard S, Richter JR, Rodriguez C, Cho HJ, Chari A, Jagannath S, Rossi A, Parekh SS. Leveraging wearable devices for remote patient monitoring facilitate earlier CRS detection following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM): Early results from an IIT. Clinical Lymphoma Myeloma and Leukemia. 2023; 23:S58.
Early detection of CRS after CAR-T therapy using wearable monitoring devices: Preliminary results in relapsed/ refractory multiple myeloma (RRMM).
Insight: Current Health monitoring can detect signs of cytokine release syndrome a median of 3 hours before standard nursing care in an interim analysis of patients receiving CAR-T therapy for relapsed/refractory multiple myeloma.
Rajeeve S, Wilkes M, Zahradka N, Serebyrakova K, Kappes K, Jackson H, Buchenholz N, Agte S, Thibaud S, Sanchez LJ, Richard S, Richter JR, Rodriguez C, Cho HJ, Chari A, Jagannath S, Rossi A, Parekh SS. Early detection of CRS after CAR-T therapy using wearable monitoring devices: Preliminary results in relapsed/ refractory multiple myeloma (RRMM). Journal of Clinical Oncology 2023 41:16_suppl, e13626-e13626.
The impact of portability of wearable monitoring device on study retention and participant experience in patients with unresectable stage III NSCLC treated with standard-of-care durvalumab: Learnings from the ON TRAX pilot study
Insight: Explores the technology-participation association. Updating wearable technology to a smaller form factor mid-trial can improve length of participation.
Cotarla I, Zahradka N, Irabor OC, Brannman L, Bhosale A, Coldiron A, Murphy K, Wilkes M, Gray JE. The impact of portability of wearable monitoring device on study retention and participant experience in patients with unresectable stage III NSCLC treated with standard-of-care durvalumab: Learnings from the ON TRAX pilot study. Journal of Clinical Oncology 2023 41:16_suppl, e20562-e20562.
Promoting digital health equity through remote patient monitoring: A feasibility study.
Insight: RPM has promise to deliver high quality and equitable cancer care. Feasibility of RPM program in patients with cancer at a large urban medical center serving racially and socioeconomically diverse population.
Kessler A, Besculides M, Kisswany C, Liu M, Berkalieva A, Mazumdar M, Smith C, Gorbenko KO. Promoting digital health equity through remote patient monitoring: A feasibility study. Journal of Clinical Oncology 2022 40:28_suppl, 441-441.
A feasibility study of remote patient monitoring among vulnerable patients with cancer.
Insight: Explores the feasibility of RPM in patients with cancer. Weekly census of 9-10 patients undergoing RPM. Mean length of monitoring was 21.7 days with an average of 3 clinical alarms per week.
Kessler A, Besculides M, Kisswany C, Liu M, Berkalieva A, Mazumdar M, Smith C, Gorbenko KO. A feasibility study of remote patient monitoring among vulnerable patients with cancer. Journal of Clinical Oncology 2022 40:16_suppl, e13652-e13652.
A Phase 4 Study to Evaluate Outpatient Blinatumomab in Patients With Minimal/Measurable Residual Disease (MRD) Positivity (+) of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
Insight: Explores the feasibility of a virtual immunotherapy program. CH can be feasibly used to deliver immunotherapy with reduced hospital LOS.
Khan S, Mori S, Jeyakumar D et al. A Phase 4 Study to Evaluate Outpatient Blinatumomab in Patients With Minimal/Measurable Residual Disease (MRD) Positivity (+) of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL). Journal of Clinical Oncology 2021 39:15_suppl, TPS7051-TPS7051.
Venous thromboembolism risk, physical activity, and outcomes in a UK Virtual Ward: Preliminary findings.
Insight: Risks of VTE may be reduced in HAH. Patients took ~100 more steps/day (~10% increase) than reported in inpatient setting.
Pugmire J, Whelan VR, Smith V, Harvey-Porter S, Wilkes M, Zaniello B, Zahradka N. Venous thromboembolism risk, physical activity, and outcomes in a UK Virtual Ward: Preliminary findings. Hospital at Home User Group Annual Meeting, 2025.
Remote monitoring after elective colorectal surgery, a pilot study.
Insight: Remote home monitoring is a safe, feasible, and well-liked option for patients undergoing minimally invasive colorectal surgery in rural areas. Complex disease, compensated morbidities, and conversion to open surgery were not contraindications to early discharge.
Dornbush C, Mishra A, Hrabe J, Guyton K, Axelrod D, Blum J, Gribovskaja-Rupp I. Remote monitoring after elective colorectal surgery, a pilot study. Surgery. 2025 Mar;179:108791.
A 2-Year Retrospective Clinical Evaluation of a Novel Virtual Ward Model.
Insight: A retrospective analysis of 1835 virtual ward admissions yielded acceptable clinical outcomes, was safe with no serious adverse events or negative impact on mortality rate. Patient adherence to the technology and satisfaction with the service were high.
Pugmire J, Ashish A, Chadwick A, Wilkes M, Meekin D, Zaniello B, Zahradka N. A 2-Year Retrospective Clinical Evaluation of a Novel Virtual Ward Model. J Prim Care Community Health. 2025 Jan;16:21501319251326750.
Surgical care through virtual wards; a new model of care for surgical inpatients.
Insight: Surgical inpatients can be successfully managed from their homes. This virtual ward service demonstrating good adherence, bed days saved, minimal hospital returns, and no adverse outcomes in both older and younger patients.
Ashish A, Fani M, Mackenzie N, Asaad P, Zahradka N, Zaniello B, Pugmire J. Surgical care through virtual wards; a new model of care for surgical inpatients. Perioperative Care of Older People Undergoing Surgery. British Geriatrics Society 2024.
Maximizing the indirect benefits of hospital at home.
Insight: Benefits of Hospital at Home. Reports on measures that often receive less attention than in traditional program goals such as enhanced staff engagement, increased patient mobility, actionable insights from continuous data, and improved quality of care at the system-level.
Goldsmith K, Hennefer D, Zahradka N. Maximizing the indirect benefits of hospital at home. AAHCM 2024.
Remote monitoring differences in Hospital at Home programmes for heart failure and chronic obstructive pulmonary disease.
Insight: Differences between hospital at home programs. In this sample, heart failure HaH programs had a higher volume of alarms compared to COPD HaH programs. This could have implications for staff to patient ratio.
Pugmire J, Wilkes M, Zaniello B, Kramer A, Zahradka N. Remote monitoring differences in Hospital at Home programmes for heart failure and chronic obstructive pulmonary disease. UK Hospital at Home Society Conference 2024.
Hospital Is Not the Home: Lessons From Implementing Remote Technology to Support Acute Inpatient and Transitional Care in the Home in the United States and United Kingdom.
Insight: Key lessons for implementing home monitoring. Viewpoint article based on our collective experience from CH deployments in the US and UK, showcasing our expertise in remote monitoring implementation.
Wilkes M, Kramer A, Pugmire J, Pilkington C, Zaniello B, Zahradka N Hospital Is Not the Home: Lessons From Implementing Remote Technology to Support Acute Inpatient and Transitional Care in the Home in the United States and United Kingdom. J Med Internet Res 2024;26:e58888.
Geriatric patients in virtual wards; technology adoption style, ease of use, and adherence to remote monitoring technology.
Insight: Showed older adults (75+ years) are highly adherent and very able to use Current Health technology.
Pugmire J, Wilkes M, Kramer A, Zaniello B, Zahradka N. Geriatric patients in virtual wards; technology adoption style, ease of use, and adherence to remote monitoring technology. 2024 British Geriatric Society Spring Meeting.
The relationship between perceived ease of use and adherence to remote monitoring tasks in patients receiving NHS virtual care services.
Insight: Explores the factors that influence RPM adherence. Perceived ease of use may influence a patient’s adherence to tasks they need to complete while being remotely monitored.
Pugmire J, Wilkes M, Kramer A, Zaniello B, Zahradka N. The relationship between perceived ease of use and adherence to remote monitoring tasks in patients receiving NHS virtual care services. UK Society for Behavioural Medicine Conference 2024.
Temporal trends in virtual care data may influence program staffing and design.
Insight: Analyzes temporal alarm distribution. Highest clinical workload is on weekdays between 8am-8pm. 10% of patients contributed 50% of the alarms. Prompting patients in the afternoon to charge their wearable and wear it overnight may improve data quality and avoid disturbing patients for no data. Consider a scheduled prompt on Day 6.
Wilkes M, Pugmire J, Wolfberg A, Zahradka N. Temporal trends in virtual care data may influence program staffing and design. ATA 2023.
A pilot study evaluating same-day discharge supported by remote patient monitoring after laparoscopic sleeve gastrectomy.
Insight: Laparoscopic bariatric surgery with same-day discharge. Retrospective case control study of patients undergoing laparoscopic sleeve gastrectomy (SG), comparing same day surgery with RPM to patients admitted to the hospital for SG during this time.
Schaffner TJ, Wilkes M, Laverty R, Schwab SD, Zahradka N, Pugmire J, Yourk D, Masella PC, Walter R. A pilot study evaluating same-day discharge supported by remote patient monitoring after laparoscopic sleeve gastrectomy. 2023 ACS Quality and Safety.
Variability and day-to-night differences in continuously measured vital signs in hospital at home, and their implications for alarm settings.
Insight: Analyzes variability in continuous vital signs in HAH. Vital signs were statistically significant between day and night for patients with COPD and CHF but differences were not clinically significant. The complexity of day/night alarms outweighed the potential benefits.
Kramer A, Zahradka N, Wilkes M. Variability and day-to-night differences in continuously measured vital signs in hospital at home, and their implications for alarm settings. Hospital at Home User Group Annual Meeting, 2023.
Venous thromboembolism risk on the virtual ward.
Insight: Looks at venous thromboembolism (VTE) risk in a VW. Should VTE risk of VW patients be managed the same way as it is for acute hospital inpatients? Mobility level could help guide decision-making and future guidelines.
Thavajothy T, Dadah H, Martinovic J, et al. P150 Venous thromboembolism risk on the virtual ward. Thorax 2023;78:A198.
Management of community acquired pneumonia in a virtual ward setting.
Insight: Community acquired pneumonia (CAP) patients can be safely managed in a VW setting thereby easing pressures on acute inpatient beds.
Bishop E, Martinovic J, Whelan R, et al. P226 Management of community acquired pneumonia in a virtual ward setting. Thorax 2023;78:A249.
Management of asthma on the virtual ward.
Insight: Asthma patients that meet certain inclusion criteria can safely be managed in a VW setting, thereby easing pressures in all aspects of hospital admissions.
Whelan R, Ward D, Martinovic J, et a. lP231 Management of asthma on the virtual ward. Thorax 2023;78:A251-A252.
Enhancing respiratory capacity using a technology enabled virtual ward.
Insight: Service blueprint of respiratory virtual ward serving a dispersed population across a rural geography. Technology enabled virtual wards can improve operational efficiency and deliver financial benefits.
Melville MC, Thurston A, Mackay TW, Rabinovich R, Kelly CA. Enhancing respiratory capacity using a technology enabled virtual ward. DigiFest23.
The impact of a hybrid hospital at home program in reducing subacute rehabilitation referrals.
Insight: Health outcomes associated with care at home. Subacute rehabilitation referrals were significantly lower in patients cared for at home vs. in hospital, possibly due to increased mobility and comfort in the home.
Yadav RR, Mahyoub MA, Capriotti MW, Berio-Dorta RL, Dougherty K, Shukla A. The impact of a hybrid hospital at home program in reducing subacute rehabilitation referrals. Risk Management and Healthcare Policy. 2023;16:2223-2235.
Successful implementation of round-the-clock care in a Virtual Ward during the COVID-19 pandemic: service delivery, technology and lessons for the future.
Insight: Deployment of a virtual ward at NNUH. Current Health was successfully implemented and scaled as a Virtual Ward, building capacity and offering 24/7 nursing care for 852 patients at NNUH in the first 12 months. 100% of surveyed patients said they would recommend the VW to family and friends.
Wells EC, Lever Taylor J, Wilkes M, Prosser-Snelling E. Successful implementation of round-the-clock care in a Virtual Ward during the COVID-19 pandemic: service delivery, technology and lessons for the future. British Journal of Nursing 2022 Nov 10;31(20):1040-1044.
Time spent on remote patient monitoring in a hospital at home program.
Insight: Work effort of virtual nursing in a Hospital at Home program. Expert virtual nursing in a HaH environment can reduce alarm fatigue, efficiently supervise patients, and significantly reduce demands on program staff.
Zahradka N, Michaelidis C, Bajracharya A, Szymanski C, Rolli D, Wolfberg A. Time spent on remote patient monitoring in a hospital at home program. Hospital at Home User Group Annual Meeting, 2022 Oct 27.
The Impact of Clinician-to-Patient Deployment of Remote Monitoring Technology on Wearable Activation and Adherence.
Insight: Patients given their kit in person by the HCP were more likely to activate their kit on the day of receipt and had a more desirable distribution of adherence. For prompt activation and to maximize adherence, consider delivering devices in person, or adding additional support if receiving kit via a third party.
Wilkes M, Pugmire J, Wolfberg A, Zahradka N. The Impact of Clinician-to-Patient Deployment of Remote Monitoring Technology on Wearable Activation and Adherence. American Academy of Home Care Medicine 2022 Oct 15.
Rapid Evaluation of Croydon Virtual Ward.
Insight: Successful implementation of a virtual ward program in Croydon. In a predominantly elderly population, 89% found the kit easy to use. Estimated cost saving of £742.44 per VW patient compared to matched controls. Identified serious underlying pathology while patient at home (inc. 5x new pulmonary embolus, 2x heart arrhythmias, 2x OSA, 1x atrial myxoma).
Health Innovation Network. Rapid Evaluation of Croydon Virtual Ward. NHS Frontiers 2021 Dec.
A randomized, controlled trial of in-hospital use of virtual reality to reduce preoperative anxiety prior to cardiac surgery.
Insight: Treatment of older adults with an immersive virtual reality experience before cardiac surgery can significantly reduce overall anxiety.
Subramaniam T, Dearani J, Stulak J, Lahr B, Lee A, Miller J. A randomized, controlled trial of in-hospital use of virtual reality to reduce preoperative anxiety prior to cardiac surgery. May Clinic Proceedings. 2025; 100(2): 220-234.
Evaluation of a remote patient monitoring hypertension program with telehealth pharmacist management in nephrology clinic patients.
Insight: Self-measured blood pressure significantly improved blood pressure control, with SMBP control <140/90 increasing from 30% to 74% over 12 months. Hospitalizations decreased significantly post-enrollment.
Bitton N; Krumich C; Webster L; Andersen S; Quattrocchi J; Gendy F; Namjouyan K; Bucaloiu I; Jones T; Bali A; Fry E; Chang A. Evaluation of a remote patient monitoring hypertension program with telehealth pharmacist management in nephrology clinic patients. Hypertension 2024; 81 (Suppl 1): AMP11.
Patient adherence to remote monitoring measures deployed in heart failure management programs.
Insight: RPM wearable adherence report. Wearable [77.5 (4594)] % and weight [89 (60 100)] % had highest adherence, BP [44 (22-81)] % and surveys [11 (0-51)] % lowest. Engagement strategies, targeted to the least adherent measures, may improve data completeness.
Zahradka N, Pugmire J, Wolfberg A, Wilkes M. Patient adherence to remote monitoring measures deployed in heart failure management programs. J Am Coll Cardiol. 2023 Mar, 81 (8_Supplement) 2232.
Assessing patient and clinician needs and preferences to refine a telehealth delivered cardiac rehabilitation program within a diverse real-world hospital setting using a theory-informed, mixed-methods, multilevel stakeholder approach.
Insight: Assessment of patient and provider needs and preferences in cardiac rehabilitation. Prospective mixed-methods approach to ensure the New York Presbyterian telehealth enhanced hybrid cardiac rehabilitation program continues to meet the needs and preferences of their endusers (i.e., patients and providers).
Serafini MA, Kenner-DeNoia A, Pugmire J, Diamond ME, Munoz M, Ludmir D, Fraser A, Kalra R, Moise N, Zahradka N, Duran A. Assessing patient and clinician needs and preferences to refine a telehealth delivered cardiac rehabilitation program within a diverse real-world hospital setting using a theory-informed, mixed-methods, multilevel stakeholder approach. The Science of Dissemination and Implementation in Health 2023.
Healthcare provider experiences of deploying a continuous remote patient monitoring pilot program during the COVID-19 pandemic: a structured qualitative analysis.
Insight: Qualitative analysis of COVID program leaders. Participants believed buy-in from leadership and HCPs were critical for successful program implementation. HCP participants showed qualities of enthusiasm, persistence with problem solving and expectation management, and a belief in the CRPM program.
Pugmire J, Wilkes M, Wolfberg A, Zahradka N. Healthcare provider experiences of deploying a continuous remote patient monitoring pilot program during the COVID-19 pandemic: a structured qualitative analysis. Front Digit Health. 2023 Jun 28;5:1157643.
Assessment of remote vital sign monitoring and alarms in a real-world healthcare at home dataset.
Insight: RPM Alarm analysis. Vital sign thresholds closest to the normal range, smaller aggregation window, and/or individual vital sign rule were most likely to increase alarm rates. These settings are most amenable to modification to increase specificity and minimize the potential of alarm fatigue.
Zahradka N, Geoghan S, Watson H, Goldberg E, Wolfberg A, Wilkes M. Assessment of remote vital sign monitoring and alarms in a real-world healthcare at home dataset. Bioengineering 2023 10, 37.
Remote patient monitoring to facilitate same-day discharge following primary laparoscopic sleeve gastrectomy: a pilot evaluation.
Insight: Laparoscopic bariatric surgery with same-day discharge. Same day discharge with CH incurred incremental savings of up to $12,000 per procedure, compared to inpatients. Readmission rates were similar (10 vs 7.5 %, p > 0.05). RPM wsearable and blood pressure adherence was found to be 97 and 80 %, respectively. RPM alarm rates were 0.5 (0 – 1.3) per patient for each 24-hour home monitoring period.
Schaffner TJ, Wilkes M, Laverty R, Schwab SD, Zahradka N, Yourk D, Masella PC, Walter R. Remote patient monitoring to facilitate same-day discharge following primary laparoscopic sleeve gastrectomy: a pilot evaluation. Surg Obes Relat Dis. 2023 Sep;19(9):1067-1074.
Financial and Clinical Impact of Virtual Care During the COVID-19 Pandemic: Difference-in-Differences Analysis.
Insight: DHA COVID E.D. diversion program saved $2.3M. Centers with the program had a 12% lower length of stay averaged across all COVID-19 patients. This saved approximately $2,000 per patient, and $2.3M across the health system. Median wearable adherence was 85% (IQR 63-94%). 27 (11.4%) were escalated to a physical hospital bed, with no increases in 30-day readmissions or E.D. visits.
Walter RJ, Schwab SD, Wilkes M, Yourk D, Zahradka N, Pugmire J, Wolfberg A, Merritt A, Boster J, Loudermilk K, Hipp SJ, Morris MJ. Financial and Clinical Impact of Virtual Care During the COVID-19 Pandemic: Difference-in-Differences Analysis. J Med Internet Res. 2023 Jan 25;25:e44121.
Use of remote patient monitoring kits to reduce hospitalization and mortality rates for patients with heart failure.
Insight: HF RPM program associated with lower 30-day and 90day rates of HF hospitalization. Single-center, retrospective chart review evaluating hospitalization of patients before and after implementing a HF RPM program.
Ehringer DS, Mughmaw TE, Albers RC. Use of remote patient monitoring kits to reduce hospitalization and mortality rates for patients with heart failure. American Journal of Health-System Pharmacy, 2023; zxad292. HF RPM program associated with lower 30-day and 90-day rates.
Implementation of wireless continuous vital sign monitoring after cesarean delivery in Uganda.
Insight: Virtual post-cesarean monitoring in Uganda. 1,882 women were recruited after c-section, over 26 weeks, 82% (n=1551) had CH. Median LOS of 24 hrs Mean of 0.4 ±1.2 alerts per 8-hr shift. Clinicians acknowledged alerts within 5, 15, and 30 minutes for 43%, 20% and 22% of alerts received, respectively. Wireless remote patient monitoring can be implemented in a busy tertiary maternity center in Uganda.
Boatin, AA, Del Cueto P, Bebell LM, Lugobe HM, Martinez K, Mohamed S, Wylie BJ, Mugyenyi G, Musinguzi N, Metlay J, Hedt-Gauthier B,Haberer J, Ngonzi J. Implementation of wireless continuous vital sign monitoring after cesarean delivery in Uganda. SMFM 2023.
A Structured Qualitative Evaluation Finds that Nurses Experience an Improved Sense of Connection with their Patients in a Virtual COVID-19 Pilot Program.
Insight: Influence virtual care on HCPpatient relationship. HCPs caring for patients reported an enhanced sense of connection with their patients as a direct result of using the Current Health platform during the COVID-19 pandemic.
Pugmire J, Wilkes M, Wolfberg A, Walters R, Zahradka N. A Structured Qualitative Evaluation Finds that Nurses Experience an Improved Sense of Connection with their Patients in a Virtual COVID-19 Pilot Program. American Academy of Home Care Medicine 2022 Oct 15.
Patient and staff satisfaction and confidence in a continuous wearable monitor to detect respiratory depression following neuraxial opioid use for postoperative pain relief after cesarean section.
Insight: Post-cesarean monitoring outcomes. Mothers ‘strongly agreed’ that CH did not interfere with sleep and allowed them to breastfeed and bond with their baby better than standard of care. Staff had confidence in CH and its ability to match (and potentially exceed) standard monitoring.
Kett A, Zapolski A, Lever Taylor J, Wilkes M, Zahradka N. Patient and staff satisfaction and confidence in a continuous wearable monitor to detect respiratory depression following neuraxial opioid use for postoperative pain relief after cesarean section. Society for Obstetric Anesthesia and Perinatology 2022 May 15 2022.
Remote care and triage of obstetric patients with COVID-19 in the community: operational considerations.
Insight:Implementing a COVID virtual care program for OB patients. Patients stayed half as long, were 3x less likely to need hospital admission and 30x less likely to need critical care than the national average (Vousden, AOGS, 2022). The service offered antenatal care for women who were self-isolating, vulnerable, or otherwise struggling to access care. Patients gave maximal, or near maximal scores for information, confidence, ease of use, confidence, and overall service.
Bircher C, Wilkes M, Zahradka N, Wells EC, Prosser-Snelling E. Remote care and triage of obstetric patients with COVID-19 in the community: operational considerations. BMC Pregnancy and Childbirth 2022 Jul 8;22(1):550.
Deployment of an End-to-End Remote, Digitalized Clinical Study Protocol in COVID-19: Process Evaluation.
Insight: Deployment of a virtual COVID trial. CH can establish a remote, digital clinical trial, from concept to recruitment, with wearable adherence of 70% and survey adherence of 80%.
Zahradka N, Pugmire J, Lever Taylor J, Wolfberg A, Wilkes M. Deployment of an End-to-End Remote, Digitalized Clinical Study Protocol in COVID-19: Process Evaluation. JMIR Form Res. 2022 Jul;6(7):e37832.
Participant Experiences of a COVID-19 Virtual Clinical Study Using the Current Health Remote Monitoring Platform: Case Study and Qualitative Analysis.
Insight: Virtual trial considerations. Current Health rigorously assessed usability and processes in a digital clinical trial. Strong positive quotes around ease of use and quality of service.
Pugmire J, Lever Taylor J, Wilkes M, Wolfberg A, Zahradka N. Participant Experiences of a COVID-19 Virtual Clinical Study Using the Current Health Remote Monitoring Platform: Case Study and Qualitative Analysis. JMIR Form Res. 2022 Jul;6(7):e37567.
The challenges of decentralized recruitment during the COVID-19 pandemic.
Insight: Virtual trial implementation. Current Health can establish a remote, digital clinical trial, from conception to recruitment, and understands its challenges.
Lever Taylor J, Wilkes M, Pugmire J, Zahradka N. The challenges of decentralized recruitment during the COVID-19 pandemic. Society of Clinical Research Associates (SOCRA) Annual Conference 2021 Sep 2225.
Physiological deterioration in the Emergency Department: The SNAP40-ED study.
Insight: Faster detection of clinical deterioration in the E.D. Current Health detected deterioration 24 mins earlier than wired monitoring and 65 mins earlier than manual vital signs. 85% found the device more comfortable than standard monitoring. 70% felt more confident wearing the device compared to standard monitoring.
Reed MJ, O’Brien R, Black PL, Lewis S, Ensor H, Wilkes M, McCann C, Whiting S. Physiological deterioration in the Emergency Department: The SNAP40-ED study. Emergency Care Journal 2021;17:9711.
Acceptability of a wearable continuous vital sign monitor for post–operative monitoring after cesarean delivery in Uganda.
Insight: Virtual post-cesarean monitoring described. CH supported a large, complex trial in an LMIC through all stages of implementation, recruitment, and data collection. 95% of participants agreed ‘comfortable’ or ‘very comfortable’. 89% agreed ‘compatible with breast feeding’.98 % would ‘use again’ or ‘recommend to other women’.
Boatin, AA, Lugobe HM, Bebell LM; Ketchum R; Wylie BJ; Mugyenyi G; Martinez K, Psaros C; Haberer, JE; Ngonzi, J. Acceptability of a wearable continuous vital sign monitor for post–operative monitoring after cesarean delivery in Uganda. Int J Gynecol Obstet. 2021;155(Suppl. 2):268.
Wearable technology: COVID-19 and the rise of remote clinical monitoring.
Insight: Current Health has specialist insight into hospital at home and wearable tech.
Best J. Wearable technology: COVID-19 and the rise of remote clinical monitoring. BMJ 2021;372:n413.
Current Health provides the clinical and operational infrastructure for safe, scalable delivery of CAR-T, bispecifics, and other advanced therapies in community and home settings.
